VPS45 Antibody

Product Specifications

Background

Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. [provided by RefSeq].

NCBI Gene ID

11311

Swiss Prot

Q9NRW7

Accession Number

Q9NRW7

Host

Rabbit

Reactivity

Human

Immunogen

This VPS45 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 461-489 amino acids from the C-terminal region of human VPS45.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

65 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

VPS45

NCBI Official Name

Vacuolar protein sorting-associated protein 45

NCBI Organism

Homo sapiens

Background Reference 01

Rahajeng, J., et al. Exp. Cell Res. 316 (5) :859-874 (2010)

Background Reference 02

Kim, B.Y., et al. Biochem. Biophys. Res. Commun. 311 (3) :577-582 (2003)

Background Reference 03

Dulubova, I., et al. EMBO J. 21 (14) :3620-3631 (2002)

Background Reference 04

De Renzis, S., et al. Nat. Cell Biol. 4 (2) :124-133 (2002)

Other Product Names

Vacuolar protein sorting-associated protein 45, h-VPS45, hlVps45, VPS45, VPS45A, VPS45B

Tested Applications

Protein ID

23396937

Physical Properties

Liquid

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