PMP22 Antibody
Product Specifications
Background
This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies.
NCBI Gene ID
5376
Swiss Prot
Q01453
Accession Number
Q01453
Host
Rabbit
Reactivity
Human
Immunogen
This PMP22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from human PMP22.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
18 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PMP22
NCBI Official Name
Peripheral myelin protein 22
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010) Kohl, B., et al. Am. J. Pathol. 176 (3) :1390-1399 (2010) Kabzinska, D., et al. J. Appl. Genet. 51 (2) :203-209 (2010) Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009) Stangler Herodez, S., et al. J. Int. Med. Res. 37 (5) :1626-1631 (2009)
Other Product Names
Peripheral myelin protein 22, PMP-22, Growth arrest-specific protein 3, GAS-3, PMP22, GAS3
Tested Applications
WB
Protein ID
266803
Physical Properties
Liquid
Frequently Asked Questions
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