Mouse Cdk20 Antibody

Product Specifications

Background

Cdk20 is involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160' (By similarity) . Required for high-level Shh responses in the developing neural tube. Together with BROMI, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling.

NCBI Gene ID

105278

Swiss Prot

Q9JHU3

Accession Number

Q9JHU3

Host

Rabbit

Reactivity

Mouse

Immunogen

This Mouse Cdk20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-212 amino acids from the Central region of mouse Cdk20.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

38 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Cdk20

NCBI Official Name

Cyclin-dependent kinase 20

NCBI Organism

Mus musculus

Background Reference 01

Qiu, H., et al. J. Biol. Chem. 283 (32) :22157-22165 (2008)

Background Reference 02

Wohlbold, L., et al. Cell Cycle 5 (5) :546-554 (2006)

Other Product Names

Cyclin-dependent kinase 20, CDK-activating kinase p42, CAK-kinase p42, CDK-related protein kinase PNQLARE, Cell cycle-related kinase, Cell division protein kinase 20, Cyclin-dependent protein kinase H, Cyclin-kinase-activating kinase p42, Cdk20, Ccrk, Cdch