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CAPG Antibody

Product Specifications

Background

This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed, but have not been fully described. [provided by RefSeq].

NCBI Gene ID

822

Swiss Prot

P40121

Accession Number

P40121

Host

Rabbit

Reactivity

Human

Immunogen

This CAPG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-209 amino acids from the Central region of human CAPG.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

38 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CAPG

NCBI Official Name

Macrophage-capping protein

NCBI Organism

Homo sapiens

Background Reference 01

Li, M.X., et al. Med. Oncol. 27 (1) :134-144 (2010)

Background Reference 02

Burillo, E., et al. Atherosclerosis 207 (1) :32-37 (2009)

Background Reference 03

Zhang, R., et al. Am. J. Respir. Cell Mol. Biol. 41 (4) :467-475 (2009)

Background Reference 04

Hubert, T., et al. Biochem. Biophys. Res. Commun. 380 (1) :166-170 (2009)

Other Product Names

Macrophage-capping protein, Actin regulatory protein CAP-G, CAPG, AFCP, MCP

Tested Applications

WB

Protein ID

313104088

Physical Properties

Liquid

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