STMN2 Antibody

Product Specifications

Background

This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6.

NCBI Gene ID

11075

Swiss Prot

Q93045

Accession Number

Q93045

Host

Rabbit

Reactivity

Human

Immunogen

This STMN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-173 amino acids from the C-terminal region of human STMN2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Chicken, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

21 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

STMN2

NCBI Official Name

Stathmin-2

NCBI Organism

Homo sapiens

Background Reference 01

Paradis, V., et al. Am. J. Pathol. 177 (4) :1791-1797 (2010)

Background Reference 02

Rowe, D.D., et al. Brain Res. (2010) In press :

Background Reference 03

Alves, M.M., et al. Hum. Mol. Genet. 19 (18) :3642-3651 (2010)

Background Reference 04

Xu, H., et al. J. Biol. Chem. 285 (6) :3548-3553 (2010)

Other Product Names

Stathmin-2, Superior cervical ganglion-10 protein, Protein SCG10, STMN2, SCG10, SCGN10

Tested Applications

Protein ID

51704330

Physical Properties

Liquid

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