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RPS14 Antibody

Product Specifications

Background

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S11P family of ribosomal proteins. It is located in the cytoplasm. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. In Chinese hamster ovary cells, mutations in this gene can lead to resistance to emetine, a protein synthesis inhibitor. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

NCBI Gene ID

6208

Swiss Prot

P62263

Accession Number

P62263

Host

Rabbit

Reactivity

Human

Immunogen

This RPS14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-147 amino acids from the C-terminal region of human RPS14.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Hamster, Drosophila, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

16 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RPS14

NCBI Official Name

40S ribosomal protein S14

NCBI Organism

Homo sapiens

Background Reference 01

Oliva, E.N., et al. Eur. J. Haematol. 85 (3) :231-235 (2010)

Background Reference 02

Borze, I., et al. Cancer Genet. Cytogenet. 197 (2) :166-173 (2010)

Background Reference 03

Quarello, P., et al. Haematologica 95 (2) :206-213 (2010)

Background Reference 04

Valencia, A., et al. Blood 112 (3), 918 (2008) :

Other Product Names

40S ribosomal protein S14, RPS14

Tested Applications

WB

Protein ID

50403752

Physical Properties

Liquid

Frequently Asked Questions

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