NFYC Antibody

Product Specifications

Background

This gene encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

4802

Swiss Prot

Q13952

Accession Number

Q13952

Host

Rabbit

Reactivity

Human

Immunogen

This NFYC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-129 amino acids from the N-terminal region of human NFYC.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

50 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NFYC

NCBI Official Name

Nuclear transcription factor Y subunit gamma

NCBI Organism

Homo sapiens

Background Reference 01

Ichikawa, S., et al. J. Bone Miner. Res. 25 (8) :1821-1829 (2010)

Background Reference 02

Murai-Takeda, A., et al. J. Biol. Chem. 285 (11) :8084-8093 (2010)

Background Reference 03

Ceribelli, M., et al. J. Biol. Chem. 284 (49) :34189-34200 (2009)

Background Reference 04

Yamanaka, K., et al. Genomics 94 (4) :219-227 (2009)

Other Product Names

Nuclear transcription factor Y subunit gamma, CAAT box DNA-binding protein subunit C, Nuclear transcription factor Y subunit C, NF-YC, Transactivator HSM-1/2, NFYC