CD200R1 Antibody

Product Specifications

Background

This gene encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner. Alternative splicing of this gene results in multiple transcript variants.

NCBI Gene ID

131450

Swiss Prot

Q8TD46

Accession Number

Q8TD46

Host

Rabbit

Reactivity

Human

Immunogen

This CD200R1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-303 amino acids from the C-terminal region of human CD200R1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

37 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CD200R1

NCBI Official Name

Cell surface glycoprotein CD200 receptor 1

NCBI Organism

Homo sapiens

Background Reference 01

Luo, X.G., et al. Neurochem. Res. 35 (4) :540-547 (2010)

Background Reference 02

Mihrshahi, R., et al. J. Immunol. 183 (8) :4879-4886 (2009)

Background Reference 03

Koning, N., et al. J. Neuropathol. Exp. Neurol. 68 (2) :159-167 (2009)

Background Reference 04

Meuth, S.G., et al. J. Neuroimmunol. 194 (1-2), 62-69 (2008) :

Other Product Names

Cell surface glycoprotein CD200 receptor 1, CD200 cell surface glycoprotein receptor, Cell surface glycoprotein OX2 receptor 1, CD200R1, CD200R, CRTR2, MOX2R, OX2R