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ZFPM2 Antibody

Product Specifications

Background

The zinc finger protein encoded by this gene is a widely expressed member of the FOG family of transcription factors. The family members modulate the activity of GATA family proteins, which are important regulators of hematopoiesis and cardiogenesis in mammals. It has been demonstrated that the protein can both activate and down-regulate expression of GATA-target genes, suggesting different modulation in different promoter contexts. A related mRNA suggests an alternatively spliced product but this information is not yet fully supported by the sequence. [provided by RefSeq].

NCBI Gene ID

23414

Swiss Prot

Q8WW38

Accession Number

Q8WW38

Host

Rabbit

Reactivity

Human

Immunogen

This ZFPM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 883-911 amino acids from the C-terminal region of human ZFPM2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

128 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ZFPM2

NCBI Official Name

Zinc finger protein ZFPM2

NCBI Organism

Homo sapiens

Background Reference 01

De Luca, A., et al. Clin. Genet. (2010) In press :

Background Reference 02

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 03

Hyun, S., et al. Cell 139 (6) :1096-1108 (2009)

Background Reference 04

Rouf, R., et al. Circ. Res. 103 (5) :493-501 (2008)

Other Product Names

Zinc finger protein ZFPM2, Friend of GATA protein 2, FOG-2, Friend of GATA 2, hFOG-2, Zinc finger protein 89B, Zinc finger protein multitype 2, ZFPM2, FOG2, ZNF89B

Tested Applications

WB

Protein ID

126302543

Physical Properties

Liquid

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