RAB25 Antibody

Product Specifications

Background

RAB proteins, such as RAB25, are members of the RAS superfamily of small GTPases that are involved in membrane trafficking. Members of the RAB11 subfamily, including RAB25, control the return of internalized membrane-associated moieties to the cell surface (Caswell et al., 2007 [PubMed 17925226]) .[supplied by OMIM].

NCBI Gene ID

57111

Swiss Prot

P57735

Accession Number

P57735

Host

Rabbit

Reactivity

Mouse

Immunogen

This RAB25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-141 amino acids from the Central region of human RAB25.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rb

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

23 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RAB25

NCBI Official Name

Ras-related protein Rab-25

NCBI Organism

Homo sapiens

Background Reference 01

Cheng, J.M., et al. Int. J. Cancer 126 (12) :2799-2812 (2010)

Background Reference 02

Nam, K.T., et al. J. Clin. Invest. 120 (3) :840-849 (2010)

Background Reference 03

Caswell, P.T., et al. Dev. Cell 13 (4) :496-510 (2007)

Background Reference 04

Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

Other Product Names

Ras-related protein Rab-25, CATX-8, RAB25, CATX8

Tested Applications

Protein ID

46577696

Physical Properties

Liquid

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