RAB25 Antibody
Product Specifications
Background
RAB proteins, such as RAB25, are members of the RAS superfamily of small GTPases that are involved in membrane trafficking. Members of the RAB11 subfamily, including RAB25, control the return of internalized membrane-associated moieties to the cell surface (Caswell et al., 2007 [PubMed 17925226]) .[supplied by OMIM].
NCBI Gene ID
57111
Swiss Prot
P57735
Accession Number
P57735
Host
Rabbit
Reactivity
Mouse
Immunogen
This RAB25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-141 amino acids from the Central region of human RAB25.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rb
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
23 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
RAB25
NCBI Official Name
Ras-related protein Rab-25
NCBI Organism
Homo sapiens
Background Reference 01
Cheng, J.M., et al. Int. J. Cancer 126 (12) :2799-2812 (2010)
Background Reference 02
Nam, K.T., et al. J. Clin. Invest. 120 (3) :840-849 (2010)
Background Reference 03
Caswell, P.T., et al. Dev. Cell 13 (4) :496-510 (2007)
Background Reference 04
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Other Product Names
Ras-related protein Rab-25, CATX-8, RAB25, CATX8
Tested Applications
WB
Protein ID
46577696
Physical Properties
Liquid
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