CTBP1 Antibody
Product Specifications
Background
This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.
NCBI Gene ID
1487
Swiss Prot
Q13363
Accession Number
Q13363
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
This CTBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 413-440 amino acids from the C-terminal region of human CTBP1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
48 kDa
Fragment
Rabbit Ig
Symbol
CTBP1
NCBI Official Name
C-terminal-binding protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Roukens, M.G., et al. Nat. Cell Biol. 12 (10) :933-942 (2010)
Background Reference 02
Choi, H.J., et al. Biochem. Biophys. Res. Commun. 400 (3) :396-402 (2010)
Background Reference 03
Merrill, J.C., et al. J. Mol. Biol. 398 (5) :657-671 (2010)
Background Reference 04
Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)
Other Product Names
C-terminal-binding protein 1, CtBP1, 111-, CTBP1, CTBP
Tested Applications
WB, IF
Protein ID
6014741
Physical Properties
Liquid
Curated Selection
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