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PFN2 Antibody

Product Specifications

Background

The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene.

NCBI Gene ID

5217

Swiss Prot

P35080

Accession Number

P35080

Host

Rabbit

Reactivity

Human

Immunogen

This PFN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 110-139 amino acids from the C-terminal region of human PFN2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

15 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PFN2

NCBI Official Name

Profilin-2

NCBI Organism

Homo sapiens

Background Reference 01

Shao, J., et al. Mol. Cell. Biol. 28 (17) :5196-5208 (2008)

Background Reference 02

Rikova, K., et al. Cell 131 (6) :1190-1203 (2007)

Background Reference 03

Xu, J., et al. Cell. Signal. 19 (7) :1575-1582 (2007)

Background Reference 04

Stelzl, U., et al. Cell 122 (6) :957-968 (2005)

Other Product Names

Profilin-2, Profilin II, PFN2

Tested Applications

WB

Protein ID

20178322

Physical Properties

Liquid

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