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NCS1 Antibody

Product Specifications

Background

NCS1 is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. NCS1 regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. This protein is thought to be associated with secretory granules and may be involved in the regulation of neurosecretion.

NCBI Gene ID

23413

Swiss Prot

P62166

Accession Number

P62166

Host

Rabbit

Reactivity

Human

Immunogen

This NCS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-144 amino acids from the Central region of human NCS1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse, Rat, Xenopus

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

22 kDa

Fragment

Rabbit Ig

Symbol

NCS1

NCBI Official Name

Neuronal calcium sensor 1

NCBI Organism

Homo sapiens

Background Reference 01

Koh, P.O., et al., Proc. Natl. Acad. Sci. U.S.A. 100 (1) :313-317 (2003) .

Background Reference 02

Bourne, Y., et al., J. Biol. Chem. 276 (15) :11949-11955 (2001) .

Background Reference 03

Burgoyne, R.D., et al., Biochem. J. 353 (Pt 1), 1-12 (2001) .

Other Product Names

Neuronal calcium sensor 1, NCS-1, Frequenin homolog, Frequenin-like protein, Frequenin-like ubiquitous protein, NCS1, FLUP, FREQ

Tested Applications

WB, IHC-P, Flow

Protein ID

49065666

Physical Properties

Liquid

Frequently Asked Questions

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