Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Connexin 50 Antibody

Product Specifications

Background

GJA8 is a an integral membrane protein that belongs to the connexin family, alpha-type (group II) subfamily. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins. This particular connexin only forms junctional channels. GJA8 is expressed in the eye lens, and defects in GJA8 are the cause of zonular pulverulent cataract type 1 (CZP1), a form of autosomal dominant congenital cataract.

NCBI Gene ID

2703

Swiss Prot

P48165

Accession Number

P48165

Host

Rabbit

Reactivity

Human

Immunogen

This Connexin 50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-130 amino acids from the N-terminal region of human Connexin 50.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-183

Calculated Molecular Weight

48 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GJA8

NCBI Official Name

Gap junction alpha-8 protein

NCBI Organism

Homo sapiens

Background Reference 01

Shiels, A., et al., Am. J. Hum. Genet. 62 (3) :526-532 (1998) .

Background Reference 02

Church, R.L., et al., Curr. Eye Res. 14 (10) :979-981 (1995) .

Background Reference 03

Church, R.L., et al., Curr. Eye Res. 14 (3) :215-221 (1995) .

Other Product Names

Gap junction alpha-8 protein, Connexin-50, Cx50, Lens fiber protein MP70, GJA8

Tested Applications

WB

Protein ID

13124697

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Involucrin (BSA & Azide Free)
MBS6507839-01 0.1 mg

Involucrin (BSA & Azide Free)

Ask
View Details
Involucrin (BSA & Azide Free)
MBS6507839-02 5x 0.1 mg

Involucrin (BSA & Azide Free)

Ask
View Details
PC-PLD1 CRISPR Activation Plasmid (m)
sc-422300-ACT 20 µg

PC-PLD1 CRISPR Activation Plasmid (m)

Ask
View Details
anti-Histone H1
YF-PA12239 100 ug

anti-Histone H1

Ask
View Details
TTLL11 (NM_194252) Human Over-expression Lysate
LS158135 100 µg

TTLL11 (NM_194252) Human Over-expression Lysate

Ask
View Details
Mouse Monoclonal DPP8 Antibody (OTI1D2) [CoraFluor 1]
NBP2-71972CL1 0.1 mL

Mouse Monoclonal DPP8 Antibody (OTI1D2) [CoraFluor 1]

Ask
View Details