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GJB5 Antibody

Product Specifications

Background

Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) such as GJB5 are thought to play crucial functional roles associated with these channels.

NCBI Gene ID

2709

Swiss Prot

O95377

Accession Number

O95377

Host

Rabbit

Reactivity

Human

Immunogen

This GJB5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-119 amino acids from the Central region of human GJB5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

31 kDa

Fragment

Rabbit Ig

Symbol

GJB5

NCBI Official Name

Gap junction beta-5 protein

NCBI Organism

Homo sapiens

Background Reference 01

Richard, G., et al., Nat. Genet. 20 (4) :366-369 (1998) .

Other Product Names

Gap junction beta-5 protein, Connexin-311, Cx311, GJB5

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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