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CREG1 Antibody

Product Specifications

Background

The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation.

NCBI Gene ID

8804

Swiss Prot

O75629

Accession Number

O75629

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This CREG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-45 amino acids from the N-terminal region of human CREG1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

24 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CREG1

NCBI Official Name

Protein CREG1

NCBI Organism

Homo sapiens

Background Reference 01

Han, Y., et al. J. Mol. Cell. Cardiol. 48 (6) :1225-1235 (2010)

Background Reference 02

Ehret, G.B., et al. Eur. J. Hum. Genet. 17 (12) :1650-1657 (2009)

Background Reference 03

Han, Y., et al. Exp. Cell Res. 315 (19) :3301-3311 (2009)

Background Reference 04

Bian, Z., et al. J. Cell. Mol. Med. 13 (7) :1302-1313 (2009)

Other Product Names

Protein CREG1, Cellular repressor of E1A-stimulated genes 1, CREG1, CREG

Tested Applications

WB

Physical Properties

Liquid

Frequently Asked Questions

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