CREG1 Antibody
Product Specifications
Background
The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation.
NCBI Gene ID
8804
Swiss Prot
O75629
Accession Number
O75629
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This CREG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-45 amino acids from the N-terminal region of human CREG1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
24 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CREG1
NCBI Official Name
Protein CREG1
NCBI Organism
Homo sapiens
Background Reference 01
Han, Y., et al. J. Mol. Cell. Cardiol. 48 (6) :1225-1235 (2010)
Background Reference 02
Ehret, G.B., et al. Eur. J. Hum. Genet. 17 (12) :1650-1657 (2009)
Background Reference 03
Han, Y., et al. Exp. Cell Res. 315 (19) :3301-3311 (2009)
Background Reference 04
Bian, Z., et al. J. Cell. Mol. Med. 13 (7) :1302-1313 (2009)
Other Product Names
Protein CREG1, Cellular repressor of E1A-stimulated genes 1, CREG1, CREG
Tested Applications
WB
Physical Properties
Liquid
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