POU4F2 Antibody

Product Specifications

Background

POU4F2 is a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. A class IV POU-domain protein, POU4F2 is found in human retina exclusively within a subpopulation of ganglion cells where it may play a role in determining or maintaining the identities of a small subset of visual system neurons.

NCBI Gene ID

5458

Swiss Prot

Q12837

Accession Number

Q12837

Host

Rabbit

Reactivity

Human

Immunogen

This POU4F2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 311-339 amino acids from the C-terminal region of human POU4F2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

43 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

POU4F2

NCBI Official Name

POU domain, class 4, transcription factor 2

NCBI Organism

Homo sapiens

Background Reference 01

Qiu, F., et al. J. Neurosci. 28 (13) :3392-3403 (2008)

Background Reference 02

Budhram-Mahadeo, V.S., et al. Oncogene 27 (1) :145-154 (2008)

Background Reference 03

Calissano, M., et al. FEBS Lett. 581 (13) :2490-2496 (2007)

Background Reference 04

Choy, K.W., et al. Physiol. Genomics 25 (1) :9-15 (2006)

Other Product Names

POU domain, class 4, transcription factor 2, Brain-specific homeobox/POU domain protein 3B, Brain-3B, Brn-3B, POU4F2, BRN3B

Tested Applications

Protein ID

290457652

Physical Properties

Liquid

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