PMS1 Antibody
Product Specifications
Background
This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.
NCBI Gene ID
5378
Swiss Prot
P54277
Accession Number
P54277
Host
Rabbit
Reactivity
Human
Immunogen
This PMS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 694-722 amino acids from the C-terminal region of human PMS1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
106 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PMS1
NCBI Official Name
PMS1 protein homolog 1
NCBI Organism
Homo sapiens
Background Reference 01
Hong, K.W., et al. J. Hum. Genet. 55 (6) :336-341 (2010)
Background Reference 02
Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press :
Background Reference 03
Guey, L.T., et al. Eur. Urol. 57 (2) :283-292 (2010)
Background Reference 04
Hosgood, H.D. III, et al. Respir Med 103 (12) :1866-1870 (2009)
Other Product Names
PMS1 protein homolog 1, DNA mismatch repair protein PMS1, PMS1, PMSL1
Tested Applications
WB
Protein ID
1709683
Physical Properties
Liquid
Curated Selection
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