PPP2R5A Antibody
Product Specifications
Background
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily.
NCBI Gene ID
5525
Swiss Prot
Q15172
Accession Number
Q15172
Host
Rabbit
Reactivity
Mouse
Immunogen
This PPP2R5A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 418-446 amino acids from the C-terminal region of human PPP2R5A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
56 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PPP2R5A
NCBI Official Name
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
NCBI Organism
Homo sapiens
Background Reference 01
Flegg, C.P., et al. J. Biol. Chem. 285 (24) :18144-18154 (2010)
Background Reference 02
Freeman, A.K., et al. Cell Cycle 9 (4) :736-747 (2010)
Background Reference 03
Reece, K.M., et al. Biochem. Biophys. Res. Commun. 386 (4) :582-587 (2009)
Background Reference 04
Li, H., et al. Mol. Cell. Biol. 29 (3) :919-928 (2009)
Other Product Names
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform, PP2A B subunit isoform B'-alpha, PP2A B subunit isoform B56-alpha, PP2A B subunit isoform PR61-alpha, PR61alpha, PP2A B subunit isoform R5-alpha, PPP2R5A
Tested Applications
WB
Protein ID
7387496
Physical Properties
Liquid
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