AP2B1 Antibody

Product Specifications

Background

The protein encoded by this gene is one of two large chain components of the assembly protein complex 2, which serves to link clathrin to receptors in coated vesicles. The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane. Two transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

163

Swiss Prot

P63010

Accession Number

P63010

Host

Rabbit

Reactivity

Human

Immunogen

This AP2B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 517-546 amino acids from the Central region of human AP2B1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

105 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

AP2B1

NCBI Official Name

AP-2 complex subunit beta

NCBI Organism

Homo sapiens

Background Reference 01

Kahlfeldt, N., et al. J. Biol. Chem. 285 (4) :2734-2749 (2010)

Background Reference 02

Hood, F.E., et al. J. Cell. Sci. 122 (PT 13), 2185-2190 (2009) :

Background Reference 03

Grass, B., et al. Histopathology 54 (7) :873-879 (2009)

Background Reference 04

Keyel, P.A., et al. Mol. Biol. Cell 19 (12) :5309-5326 (2008)

Other Product Names

AP-2 complex subunit beta, AP105B, Adaptor protein complex AP-2 subunit beta, Adaptor-related protein complex 2 subunit beta, Beta-2-adaptin, Beta-adaptin, Clathrin assembly protein complex 2 beta large chain, Plasma membrane adaptor HA2/AP2 adaptin beta subunit, AP2B1, ADTB2, CLAPB1