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AMFR Antibody

Product Specifications

Background

Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells. The protein encoded by this gene is a glycosylated transmembrane protein and a receptor for autocrine motility factor. The receptor, which shows some sequence similarity to tumor protein p53, is localized to the leading and trailing edges of carcinoma cells.

NCBI Gene ID

267

Swiss Prot

Q9UKV5

Accession Number

Q9UKV5

Host

Rabbit

Reactivity

Human

Immunogen

This AMFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371-400 amino acids from the Central region of human AMFR.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-127

Calculated Molecular Weight

73 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

AMFR

NCBI Official Name

E3 ubiquitin-protein ligase AMFR

NCBI Organism

Homo sapiens

Background Reference 01

Joshi, B., et al. J. Biol. Chem. 285 (12) :8830-8839 (2010)

Background Reference 02

Bernardi, K.M., et al. Mol. Biol. Cell 21 (1) :140-151 (2010)

Background Reference 03

Ballar, P., et al. Int. J. Biochem. Cell Biol. 42 (1) :167-173 (2010)

Background Reference 04

Shmueli, A., et al. Biochem. Biophys. Res. Commun. 390 (3) :758-762 (2009)

Other Product Names

E3 ubiquitin-protein ligase AMFR, 632-, Autocrine motility factor receptor, AMF receptor, RING finger protein 45, gp78, AMFR, RNF45

Tested Applications

WB

Protein ID

34922250

Physical Properties

Liquid

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