USP12 Antibody

Product Specifications

Background

USP12is a deubiquitinating enzyme. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2.

NCBI Gene ID

219333

Swiss Prot

O75317

Accession Number

O75317

Host

Rabbit

Reactivity

Mouse

Immunogen

This USP12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 222-251 amino acids from the Central region of human USP12.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Xenopus, Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

43 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

USP12

NCBI Official Name

Ubiquitin carboxyl-terminal hydrolase 12

NCBI Organism

Homo sapiens

Background Reference 01

Kee, Y., et al. J. Biol. Chem. 285 (15) :11252-11257 (2010)

Background Reference 02

Asano, K., et al. Nat. Genet. 41 (12) :1325-1329 (2009)

Background Reference 03

Cohn, M.A., et al. J. Biol. Chem. 284 (8) :5343-5351 (2009)

Background Reference 04

Dunham, A., et al. Nature 428 (6982) :522-528 (2004)

Other Product Names

Ubiquitin carboxyl-terminal hydrolase 12, Deubiquitinating enzyme 12, Ubiquitin thioesterase 12, Ubiquitin-hydrolyzing enzyme 1, Ubiquitin-specific-processing protease 12, USP12, UBH1, USP12L1