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IHH Antibody

Product Specifications

Background

This gene encodes a member of the hedgehog family of secreted signaling molecules. Hedgehog proteins are essential regulators of a variety of developmental processes including growth, patterning and morphogenesis. The encoded protein specifically plays a role in bone growth an differentiation. Mutations in this gene are the cause of brachydactyly type A1 which is characterized by shortening or malformation of the phalanges. Mutations in this gene are also the cause of acrocapitofemoral dysplasia.

NCBI Gene ID

3549

Swiss Prot

Q14623

Accession Number

Q14623

Host

Rabbit

Reactivity

Human

Immunogen

This IHH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-80 amino acids from the N-terminal region of human IHH.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-107

Calculated Molecular Weight

45 kDa

Fragment

Rabbit Ig

Symbol

IHH

NCBI Official Name

Indian hedgehog protein

NCBI Organism

Homo sapiens

Background Reference 01

Meulenbelt, I., et al. Ann. Rheum. Dis. (2010) In press :

Background Reference 02

Kang, S.J., et al. Hum. Mol. Genet. 19 (13) :2725-2738 (2010)

Background Reference 03

Okada, Y., et al. Hum. Mol. Genet. 19 (11) :2303-2312 (2010)

Background Reference 04

Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :

Other Product Names

Indian hedgehog protein, IHH, HHG-2, Indian hedgehog protein N-product, Indian hedgehog protein C-product, IHH

Tested Applications

WB, IHC-P

Protein ID

33112634

Physical Properties

Liquid

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