MOV10 Antibody
Product Specifications
Background
Probable RNA helicase. Required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC) . Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. Also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV) . Interacts with small capped HDV RNAs derived from genomic hairpin structures that mark the initiation sites of RNA-dependent HDV RNA transcription.
NCBI Gene ID
4343
Swiss Prot
Q9HCE1
Accession Number
Q9HCE1
Host
Rabbit
Reactivity
Human
Immunogen
This MOV10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 260-288 amino acids from the N-terminal region of human MOV10.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=58-105
Calculated Molecular Weight
114 kDa
Fragment
Rabbit Ig
Symbol
MOV10
NCBI Official Name
Putative helicase MOV-10
NCBI Organism
Homo sapiens
Background Reference 01
El Messaoudi-Aubert, S., et al. Nat. Struct. Mol. Biol. 17 (7) :862-868 (2010) Furtak, V., et al. PLoS ONE (2), E9081 (2010) Nakano, M., et al. Biochem. Biophys. Res. Commun. 388 (2) :328-332 (2009) Haussecker, D., et al. Nat. Struct. Mol. Biol. 15 (7) :714-721 (2008) Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)
Other Product Names
Putative helicase MOV-10, Moloney leukemia virus 10 protein, MOV10, KIAA1631
Tested Applications
WB, IHC-P
Protein ID
24638063
Physical Properties
Liquid
Curated Selection
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