Actin Antibody

Product Specifications

Background

Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. ACTB/ACTC are nonmuscle cytoskeletal actins and major constituents of the contractile apparatus. Defects in ACTB are a cause of juvenile-onset dystonia. Defects in ACTC have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC) .

NCBI Gene ID

Swiss Prot

P68032

Accession Number

P68032

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Actin (ACTB/ACTC) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-67 amino acids from the N-terminal region of human Actin (ACTB/ACTC) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: C. Elegans, Drosophila, Xenopus, Chicken, Bovine, Rabbit, Rat, Zebrafish, Hamster, Monkey, Pig, Yeast

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

42 kDa

Fragment

Rabbit Ig

Symbol

ACTC1

NCBI Official Name

Actin, alpha cardiac muscle 1

NCBI Organism

Homo sapiens

Background Reference 01

Villebeck, L., Biochemistry 46 (44), 12639-12647 (2007) Avizienyte, E., Exp. Cell Res. 313 (15), 3175-3188 (2007) Bouldin, A.A., Muscle Nerve 35 (2), 254-258 (2007)