Actin Antibody
Product Specifications
Background
Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. ACTB/ACTC are nonmuscle cytoskeletal actins and major constituents of the contractile apparatus. Defects in ACTB are a cause of juvenile-onset dystonia. Defects in ACTC have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC) .
NCBI Gene ID
70
Swiss Prot
P68032
Accession Number
P68032
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This Actin (ACTB/ACTC) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-67 amino acids from the N-terminal region of human Actin (ACTB/ACTC) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: C. Elegans, Drosophila, Xenopus, Chicken, Bovine, Rabbit, Rat, Zebrafish, Hamster, Monkey, Pig, Yeast
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=58-098
Calculated Molecular Weight
42 kDa
Fragment
Rabbit Ig
Symbol
ACTC1
NCBI Official Name
Actin, alpha cardiac muscle 1
NCBI Organism
Homo sapiens
Background Reference 01
Villebeck, L., Biochemistry 46 (44), 12639-12647 (2007) Avizienyte, E., Exp. Cell Res. 313 (15), 3175-3188 (2007) Bouldin, A.A., Muscle Nerve 35 (2), 254-258 (2007)
Other Product Names
Actin, alpha cardiac muscle 1, Alpha-cardiac actin, ACTC1, ACTC
Tested Applications
WB, IHC-P, IF
Protein ID
54036697
Physical Properties
Liquid
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