PKP3 Antibody

Product Specifications

Background

This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways. [provided by RefSeq].

NCBI Gene ID

11187

Swiss Prot

Q9Y446

Accession Number

Q9Y446

Host

Rabbit

Reactivity

Human

Immunogen

This PKP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 766-794 amino acids from the C-terminal region of human PKP3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

87 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PKP3

NCBI Official Name

Plakophilin-3

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Valladares-Ayerbes, M., et al. Cancer Epidemiol. Biomarkers Prev. 19 (6) :1432-1440 (2010)

Background Reference 03

Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

Background Reference 04

Kundu, S.T., et al. Int. J. Cancer 123 (10) :2303-2314 (2008)

Other Product Names

Plakophilin-3, PKP3

Tested Applications

Protein ID

20139301

Physical Properties

Liquid

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