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TRIM27 Antibody

Product Specifications

Background

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein.

NCBI Gene ID

5987

Swiss Prot

P14373

Accession Number

P14373

Host

Rabbit

Reactivity

Human

Immunogen

This TRIM27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 453-482 amino acids from the C-terminal region of human TRIM27.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-074

Calculated Molecular Weight

58 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TRIM27

NCBI Official Name

Zinc finger protein RFP

NCBI Organism

Homo sapiens

Background Reference 01

Johnson, A.D., et al. Nat. Genet. 42 (7) :608-613 (2010)

Background Reference 02

Barcellos, L.F., et al. PLoS Genet. (10), E1000696 (2009) :

Background Reference 03

Tezel, G.G., et al. Pathol. Res. Pract. 205 (6) :403-408 (2009)

Background Reference 04

Li, X., et al. Virology 360 (2) :419-433 (2007)

Other Product Names

Zinc finger protein RFP, 632-, RING finger protein 76, Ret finger protein, Tripartite motif-containing protein 27, TRIM27, RFP, RNF76

Tested Applications

WB

Protein ID

132517

Physical Properties

Liquid

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