ARHGEF1 Antibody

Product Specifications

Background

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.

NCBI Gene ID

9138

Swiss Prot

Q92888

Accession Number

Q92888

Host

Rabbit

Reactivity

Human

Immunogen

This ARHGEF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-192 amino acids from the N-terminal region of human ARHGEF1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

102 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ARHGEF1

NCBI Official Name

Rho guanine nucleotide exchange factor 1

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Loirand, G., et al. Med Sci (Paris) 26 (6-7), 561-563 (2010) :

Background Reference 03

Takefuji, M., et al. J. Hum. Genet. 55 (1) :42-49 (2010)

Background Reference 04

Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

Other Product Names

Rho guanine nucleotide exchange factor 1, 115 kDa guanine nucleotide exchange factor, p115-RhoGEF, p115RhoGEF, Sub15, ARHGEF1

Tested Applications

Protein ID

34395524

Physical Properties

Liquid

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