LDB1 Antibody

Product Specifications

Background

LDB1 binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. May play a role in the development of motor neurons. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state (By similarity) .

NCBI Gene ID

8861

Swiss Prot

Q86U70

Accession Number

Q86U70

Host

Rabbit

Reactivity

Human

Immunogen

This LDB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 351-379 amino acids from the C-terminal region of human LDB1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Zebrafish, Chicken, Mouse, Xenopus

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

47 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

LDB1

NCBI Official Name

LIM domain-binding protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Howard, P.W., et al. Biochem. Biophys. Res. Commun. 396 (3) :674-678 (2010)

Background Reference 02

Howard, P.W., et al. Biochem. J. 429 (1) :127-136 (2010)

Background Reference 03

Bhati, M., et al. EMBO J. 27 (14) :2018-2029 (2008)

Background Reference 04

Ryan, D.P., et al. Proteins 70 (4) :1461-1474 (2008)

Other Product Names

LIM domain-binding protein 1, LDB-1, Carboxyl-terminal LIM domain-binding protein 2, CLIM-2, LIM domain-binding factor CLIM2, hLdb1, Nuclear LIM interactor, LDB1, CLIM2