PRKRIR Antibody

Product Specifications

Background

Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR) . May block the PKR-inhibitory function of P58IPK, resulting in restoration of kinase activity and suppression of cell growth.

NCBI Gene ID

5612

Swiss Prot

O43422

Accession Number

O43422

Host

Rabbit

Reactivity

Human

Immunogen

This PRKRIR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from the N-terminal region of human PRKRIR.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

88 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PRKRIR

NCBI Official Name

52 kDa repressor of the inhibitor of the protein kinase

NCBI Organism

Homo sapiens

Background Reference 01

Silva, L.K., et al. Eur. J. Hum. Genet. 18 (11) :1221-1227 (2010)

Background Reference 02

Johnatty, S.E., et al. PLoS Genet. (7), E1001016 (2010) :

Background Reference 03

Lee, J.H., et al. KoreanGastroenterol 42 (6) :484-495 (2003)

Background Reference 04

Lin, Y., et al. J. Biol. Chem. 277 (50) :47991-48001 (2002)

Other Product Names

52 kDa repressor of the inhibitor of the protein kinase, p52rIPK, 58 kDa interferon-induced protein kinase-interacting protein, p58IPK-interacting protein, Death-associated protein 4, THAP domain-containing protein 0, PRKRIR, DAP4, P52RIPK, THAP0