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Mouse Frk Antibody

Product Specifications

Background

Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation possibly by reducing its binding to NEDD4. May function as a tumor suppressor (By similarity) .

NCBI Gene ID

14302

Swiss Prot

Q922K9

Accession Number

Q922K9

Host

Rabbit

Reactivity

Mouse

Immunogen

This Mouse Frk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 464-491 amino acids from the C-terminal region of mouse Frk.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

59 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Frk

NCBI Official Name

Tyrosine-protein kinase FRK

NCBI Organism

Mus musculus

Background Reference 01

Akerblom, B., et al. Mol. Cell. Endocrinol. 270 (1-2), 73-78 (2007) :

Background Reference 02

Nishimura, M., et al. DNA Res. 11 (5) :315-323 (2004)

Background Reference 03

Sharov, A.A., et al. PLoS Biol. (3), E74 (2003) :

Background Reference 04

Cowen, M.S., et al. Alcohol. Clin. Exp. Res. 27 (8) :1213-1219 (2003)

Other Product Names

Tyrosine-protein kinase FRK, Beta-cell Src-homology tyrosine kinase, BSK, FYN-related kinase, Intestine tyrosine kinase, Frk, Bsk, Iyk

Tested Applications

WB

Physical Properties

Liquid

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