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Mouse Pdk4 Antibody

Product Specifications

Background

Pdk4 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism (By similarity) .

NCBI Gene ID

27273

Swiss Prot

O70571

Accession Number

O70571

Host

Rabbit

Reactivity

Mouse

Immunogen

This Mouse Pdk4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-110 amino acids from the N-terminal region of mouse Pdk4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

47 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Pdk4

NCBI Official Name

[Pyruvate dehydrogenase (acetyl-transferring) ] kinase isozyme 4, mitochondrial

NCBI Organism

Mus musculus

Background Reference 01

Hyvarinen, J., et al. J. Biol. Chem. 285 (18) :13646-13657 (2010)

Background Reference 02

Hwang, B., et al. Biochem. J. 423 (2) :243-252 (2009)

Background Reference 03

Hsieh, M.C., et al. J. Biol. Chem. 283 (41) :27410-27417 (2008)

Background Reference 04

Lai, L., et al. Genes Dev. 22 (14) :1948-1961 (2008)

Other Product Names

[Pyruvate dehydrogenase (acetyl-transferring) ] kinase isozyme 4, mitochondrial, Pyruvate dehydrogenase kinase isoform 4, Pdk4

Tested Applications

WB

Physical Properties

Liquid

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