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LALBA Antibody

Product Specifications

Background

This gene encodes alpha-lactalbumin, a principal protein of milk. Alpha-lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and beta 1,4-galactosyltransferase (beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transfering galactose moieties to glucose. As a monomer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding variant of alpha-lactalbumin, called HAMLET, likely induces apoptosis in tumor and immature cells.

NCBI Gene ID

3906

Swiss Prot

P00709

Accession Number

P00709

Host

Rabbit

Reactivity

Human

Immunogen

This LALBA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-68 amino acids from the Central region of human LALBA.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

16 kDa

Fragment

Rabbit Ig

Symbol

LALBA

NCBI Official Name

Alpha-lactalbumin

NCBI Organism

Homo sapiens

Background Reference 01

Tolin, S., et al. FEBS J. 277 (1) :163-173 (2010)

Background Reference 02

Rosner, H.I., et al. J. Mol. Biol. 394 (2) :351-362 (2009)

Background Reference 03

Wang, J., et al. J. Dairy Sci. 91 (12) :4466-4476 (2008)

Background Reference 04

Ramboarina, S., et al. J. Am. Chem. Soc. 130 (46) :15318-15326 (2008)

Other Product Names

Alpha-lactalbumin, Lactose synthase B protein, Lysozyme-like protein 7, LALBA, LYZL7

Tested Applications

WB, IHC-P

Protein ID

126001

Physical Properties

Liquid

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