KLK15 Antibody
Product Specifications
Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In prostate cancer, this gene has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. The gene contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms.
NCBI Gene ID
55554
Swiss Prot
Q9H2R5
Accession Number
Q9H2R5
Host
Rabbit
Reactivity
Human
Immunogen
This KLK15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-106 amino acids from the Central region of human KLK15.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=58-018
Calculated Molecular Weight
28 kDa
Fragment
Rabbit Ig
Symbol
KLK15
NCBI Official Name
Kallikrein-15
NCBI Organism
Homo sapiens
Background Reference 01
Rabien, A., et al. Int. J. Cancer 127 (10) :2386-2394 (2010)
Background Reference 02
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 03
Han, S., et al. Hum. Immunol. 71 (7) :727-730 (2010)
Background Reference 04
Gallagher, D.J., et al. Clin. Cancer Res. 16 (10) :2819-2832 (2010)
Other Product Names
Kallikrein-15, 3421-, ACO protease, KLK15
Tested Applications
WB, IHC-P
Protein ID
18202940
Physical Properties
Liquid
Curated Selection
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