KLK14 Antibody

Product Specifications

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. An additional transcript variant has been described but its full length nature has not been determined.

NCBI Gene ID

43847

Swiss Prot

Q9P0G3

Accession Number

Q9P0G3

Host

Rabbit

Reactivity

Human

Immunogen

This KLK14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human KLK14.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

29 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

KLK14

NCBI Official Name

Kallikrein-14

NCBI Organism

Homo sapiens

Background Reference 01

Klein, R.J., et al. Cancer Prev Res (Phila Pa) 3 (5) :611-619 (2010)

Background Reference 02

Hashem, N.N., et al. Int. J. Biol. Markers 25 (1) :32-37 (2010)

Background Reference 03

Emami, N., et al. Biol. Chem. 390 (9) :921-929 (2009)

Background Reference 04

Lai, J., et al. Mol. Cancer Res. 7 (1) :129-141 (2009)

Other Product Names

Kallikrein-14, hK14, 3421-, Kallikrein-like protein 6, KLK-L6, KLK14, KLKL6

Tested Applications

Protein ID

251757292

Physical Properties

Liquid

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