PTPN14 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia.

NCBI Gene ID

5784

Swiss Prot

Q15678

Accession Number

Q15678

Host

Rabbit

Reactivity

Mouse

Immunogen

This PTPN14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 862-890 amino acids from the C-terminal region of human PTPN14.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

135 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PTPN14

NCBI Official Name

Tyrosine-protein phosphatase non-receptor type 14

NCBI Organism

Homo sapiens

Background Reference 01

Au, A.C., et al. Am. J. Hum. Genet. 87 (3) :436-444 (2010)

Background Reference 02

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 03

Wyatt, L., et al. Cell Cycle 7 (15) :2290-2295 (2008)

Background Reference 04

Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)

Other Product Names

Tyrosine-protein phosphatase non-receptor type 14, Protein-tyrosine phosphatase pez, PTPN14, PEZ, PTPD2

Tested Applications

Protein ID

209572662

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

A38172-50UL 50 μL

USP46 Antibody, HRP conjugated

Ask

View Details

M2421-29X-HRP 100 µL

Matrix Metalloproteinase 3 (MMP-3, Stromelysin-1, SL-1, Transin) (BSA & Azide Free) (HRP) discontinued

Ask

View Details

GTR15140523 1 Vial

Lentiviral mouse Bbs1 shRNA (UAS) - Lentiviral mouse Bbs1 shRNA (UAS, iRFP) (100)

Ask

View Details

GA118344 1 Kit

Human C10ORF132 (GOLGA7B) activation kit by CRISPRa

Ask

View Details

NBP1-25946JF646 0.1 mL

Mouse Monoclonal Pseudomonas Aeruginosa Antibody (1001/214) [Janelia Fluor 646]

Ask

View Details