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TGIF2 Antibody

Product Specifications

Background

The protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor. The encoded protein appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. This gene is amplified and overexpressed in some ovarian cancers, and mutations in this gene can cause holoprosencephaly.

NCBI Gene ID

10052794360436

Swiss Prot

Q9GZN2

Accession Number

Q9GZN2

Host

Rabbit

Reactivity

Human

Immunogen

This TGIF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-199 amino acids from the C-terminal region of human TGIF2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

26 kDa

Fragment

Rabbit Ig

Symbol

TGIF2

NCBI Official Name

Homeobox protein TGIF2

NCBI Organism

Homo sapiens

Background Reference 01

Watanabe, T., et al. Jpn. J. Cancer Res. 93 (10) :1114-1122 (2002)

Background Reference 02

Deloukas, P., et al. Nature 414 (6866) :865-871 (2001)

Background Reference 03

Melhuish, T.A., et al. J. Biol. Chem. 276 (34) :32109-32114 (2001)

Background Reference 04

Imoto, I., et al. Biochem. Biophys. Res. Commun. 276 (1) :264-270 (2000)

Other Product Names

Homeobox protein TGIF2, 5'-TG-3'-interacting factor 2, TGF-beta-induced transcription factor 2, TGFB-induced factor 2, TGIF2

Tested Applications

WB, Flow

Protein ID

27805750

Physical Properties

Liquid

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