FZD2 Antibody

Product Specifications

Background

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The expression of the FZD2 gene appears to be developmentally regulated, with high levels of expression in fetal kidney and lung and in adult colon and ovary.

NCBI Gene ID

2535

Swiss Prot

Q14332

Accession Number

Q14332

Host

Rabbit

Reactivity

Human

Immunogen

This FZD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 534-563 amino acids from the C-terminal region of human FZD2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

64 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

FZD2

NCBI Official Name

Frizzled-2

NCBI Organism

Homo sapiens

Background Reference 01

Bazhin, A.V., et al. Cell. Mol. Life Sci. 67 (5) :817-828 (2010)

Background Reference 02

Sato, A., et al. EMBO J. 29 (1) :41-54 (2010)

Background Reference 03

Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :

Background Reference 04

Ollila, H.M., et al. Mol. Psychiatry 14 (4) :351-353 (2009)

Other Product Names

Frizzled-2, Fz-2, hFz2, FzE2, FZD2

Tested Applications

Protein ID

17433019

Physical Properties

Liquid

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