ALDH8A1 Antibody
Product Specifications
Background
ALDH8A1 belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal.
NCBI Gene ID
64577
Swiss Prot
Q9H2A2
Accession Number
Q9H2A2
Host
Rabbit
Reactivity
Mouse
Immunogen
This ALDH8A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 386-416 amino acids from the C-terminal region of human ALDH8A1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
53 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:2000
Symbol
ALDH8A1
NCBI Official Name
Aldehyde dehydrogenase family 8 member A1
NCBI Organism
Homo sapiens
Background Reference 01
Lin, M., J. Biol. Chem. 275 (51), 40106-40112 (2000)
Other Product Names
Aldehyde dehydrogenase family 8 member A1, 121-, Aldehyde dehydrogenase 12, ALDH8A1, ALDH12
Tested Applications
WB
Protein ID
74752601
Physical Properties
Liquid
Frequently Asked Questions
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