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A2M Antibody

Product Specifications

Background

Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq].

NCBI Gene ID

2

Swiss Prot

P01023

Accession Number

P01023

Host

Rabbit

Reactivity

Human

Immunogen

This A2M antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-120 amino acids from the N-terminal region of human A2M.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-991

Calculated Molecular Weight

163 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

A2M

NCBI Official Name

Alpha-2-macroglobulin

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Bruno, E., et al. Neurosci. Lett. 482 (2) :112-116 (2010)

Background Reference 03

Nalpas, B., et al. Gut 59 (8) :1120-1126 (2010)

Background Reference 04

Song, H., et al. Neurosci. Lett. 479 (2) :143-145 (2010)

Other Product Names

Alpha-2-macroglobulin, Alpha-2-M, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5, A2M, CPAMD5

Tested Applications

WB

Protein ID

308153640

Physical Properties

Liquid

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