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Mouse Tgfbr1 Antibody

Product Specifications

Background

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta.

NCBI Gene ID

21812

Swiss Prot

Q64729

Accession Number

Q64729

Host

Rabbit

Reactivity

Mouse

Immunogen

This Mouse Tgfbr1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141-169 amino acids from the Central region of mouse Tgfbr1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Human, Pig, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-980

Calculated Molecular Weight

56 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Tgfbr1

NCBI Official Name

TGF-beta receptor type-1

NCBI Organism

Mus musculus

Background Reference 01

Ghoreschi, K., et al. Nature 467 (7318) :967-971 (2010)

Background Reference 02

Kel, J.M., et al. J. Immunol. 185 (6) :3248-3255 (2010)

Background Reference 03

Droguett, R., et al. Exp. Cell Res. 316 (15) :2487-2503 (2010)

Background Reference 04

Moreno, S.G., et al. Dev. Biol. 342 (1) :74-84 (2010)

Other Product Names

TGF-beta receptor type-1, TGFR-1, ESK2, Transforming growth factor-beta receptor type I, TGF-beta receptor type I, TbetaR-I, Tgfbr1

Tested Applications

WB

Physical Properties

Liquid

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