SNRPA Antibody

Product Specifications

Background

The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation.

NCBI Gene ID

6626

Swiss Prot

P09012

Accession Number

P09012

Host

Rabbit

Reactivity

Human

Immunogen

This SNRPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 83-111 amino acids from the Central region of human SNRPA.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Pig

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

31 kDa

Fragment

Rabbit Ig

Symbol

SNRPA

NCBI Official Name

U1 small nuclear ribonucleoprotein A

NCBI Organism

Homo sapiens

Background Reference 01

Guan, F., et al. RNA 13 (12) :2129-2140 (2007)

Background Reference 02

Hall-Pogar, T., et al. RNA 13 (7) :1103-1115 (2007)

Background Reference 03

Shajani, Z., et al. J. Mol. Biol. 349 (4) :699-715 (2005)

Background Reference 04

Andersen, J.S., et al. Nature 433 (7021) :77-83 (2005)

Other Product Names

U1 small nuclear ribonucleoprotein A, U1 snRNP A, U1-A, U1A, SNRPA

Tested Applications

WB, IHC-P

Protein ID

134092

Physical Properties

Liquid

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