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HTATIP2 Antibody

Product Specifications

Background

Oxidoreductase required for tumor suppression. NAPDH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect.

NCBI Gene ID

10553

Swiss Prot

Q9BUP3

Accession Number

Q9BUP3

Host

Rabbit

Reactivity

Human

Immunogen

This HTATIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-74 amino acids from the N-terminal region of human HTATIP2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-970

Calculated Molecular Weight

27 kDa

Fragment

Rabbit Ig

Symbol

HTATIP2

NCBI Official Name

Oxidoreductase HTATIP2

NCBI Organism

Homo sapiens

Background Reference 01

Chen, X., et al. Dig. Dis. Sci. 55 (8) :2219-2226 (2010)

Background Reference 02

Fong, S., et al. BMC Cell Biol. 11, 23 (2010) :

Background Reference 03

Nakahara, J., et al. Expert Opin. Ther. Targets 13 (12) :1375-1386 (2009)

Background Reference 04

Tong, X., et al. Am. J. Pathol. 174 (5) :1931-1939 (2009)

Other Product Names

HGNC:16637

Tested Applications

WB, IHC-P

Protein ID

317373366

Physical Properties

Liquid

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