HTATIP2 Antibody
Product Specifications
Background
Oxidoreductase required for tumor suppression. NAPDH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect.
NCBI Gene ID
10553
Swiss Prot
Q9BUP3
Accession Number
Q9BUP3
Host
Rabbit
Reactivity
Human
Immunogen
This HTATIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-74 amino acids from the N-terminal region of human HTATIP2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
27 kDa
Fragment
Rabbit Ig
Symbol
HTATIP2
NCBI Official Name
Oxidoreductase HTATIP2
NCBI Organism
Homo sapiens
Background Reference 01
Chen, X., et al. Dig. Dis. Sci. 55 (8) :2219-2226 (2010)
Background Reference 02
Fong, S., et al. BMC Cell Biol. 11, 23 (2010) :
Background Reference 03
Nakahara, J., et al. Expert Opin. Ther. Targets 13 (12) :1375-1386 (2009)
Background Reference 04
Tong, X., et al. Am. J. Pathol. 174 (5) :1931-1939 (2009)
Other Product Names
HGNC:16637
Tested Applications
WB, IHC-P
Protein ID
317373366
Physical Properties
Liquid
Curated Selection
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