BRDG 1 Antibody

Product Specifications

Background

STAP1 functions as a docking protein acting downstream of Tec tyrosine kinase in B cell antigen receptor signaling. The protein is directly phosphorylated by Tec in vitro where it participates in a postive feedback loop, increasing Tec activity.

NCBI Gene ID

26228

Swiss Prot

Q9ULZ2

Accession Number

Q9ULZ2

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This BRDG 1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from the N-terminal region of human BRDG 1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

34 kDa

Fragment

Rabbit Ig

Symbol

STAP1

NCBI Official Name

Signal-transducing adaptor protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Ma, J., Atherosclerosis 191 (1), 63-72 (2007)

Background Reference 02

Beausoleil, S.A., Nat. Biotechnol. 24 (10), 1285-1292 (2006)

Background Reference 03

Gstaiger, M., Science 302 (5648), 1208-1212 (2003)

Background Reference 04

Minoguchi, M., J. Biol. Chem. 278 (13), 11182-11189 (2003)

Other Product Names

Signal-transducing adaptor protein 1, STAP-1, BCR downstream-signaling protein 1, Docking protein BRDG1, Stem cell adaptor protein 1, STAP1, BRDG1

Tested Applications

WB, IHC-P

Protein ID

62511239

Physical Properties

Liquid

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