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PTGES3 Antibody

Product Specifications

Background

Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes.

NCBI Gene ID

10728

Swiss Prot

Q15185

Accession Number

Q15185

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

This PTGES3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-73 amino acids from the Central region of human PTGES3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Immunology, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey, Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-961

Calculated Molecular Weight

19 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:2000

Symbol

PTGES3

NCBI Official Name

Prostaglandin E synthase 3

NCBI Organism

Homo sapiens

Background Reference 01

Chen, W., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (16) :7401-7406 (2010)

Background Reference 02

Lee, J.H., et al. Cancer Lett. 290 (1) :76-86 (2010)

Background Reference 03

Chadli, A., et al. J. Biol. Chem. 285 (6) :4224-4231 (2010)

Background Reference 04

Woo, S.H., et al. J. Biol. Chem. 284 (45) :30871-30880 (2009)

Other Product Names

Prostaglandin E synthase 3, Cytosolic prostaglandin E2 synthase, cPGES, Hsp90 co-chaperone, Progesterone receptor complex p23, Telomerase-binding protein p23, PTGES3, P23, TEBP

Tested Applications

WB

Physical Properties

Liquid

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