KCNMB1 Antibody

Product Specifications

Background

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the product of this gene, the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits.

NCBI Gene ID

3779

Swiss Prot

Q16558

Accession Number

Q16558

Host

Rabbit

Reactivity

Human

Immunogen

This KCNMB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-72 amino acids from the Central region of human KCNMB1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

22 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

KCNMB1

NCBI Official Name

Calcium-activated potassium channel subunit beta-1

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care (2010) In press :

Background Reference 02

Xie, M.J., et al. Am. J. Physiol., Cell Physiol. 298 (6), C1489-C1500 (2010) :

Background Reference 03

Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :

Background Reference 04

Long, X., et al. J. Biol. Chem. 284 (48) :33671-33682 (2009)

Other Product Names

Calcium-activated potassium channel subunit beta-1, BK channel subunit beta-1, BKbeta, BKbeta1, Hbeta1, Calcium-activated potassium channel, subfamily M subunit beta-1, Calcium-activated potassium channel subunit beta, Charybdotoxin receptor subunit beta-1, K (VCA) beta-1, Maxi K channel subunit beta-1, Slo-beta-1, Slo-beta, KCNMB1