Mouse Dapk3 Antibody

Product Specifications

Background

Serine/threonine kinase which acts as a positive regulator of apoptosis. Phosphorylates histone H3 on 'Thr-11' at centromeres during mitosis. Regulates myosin light chain phosphatase through phosphorylation of MYPT1 thereby regulating the assembly of the actin cytoskeleton, cell migration, invasiveness of tumor cells, smooth muscle contraction and neurite outgrowth. Involved in the formation of promyelocytic leukemia protein nuclear body (PML-NB), one of many subnuclear domains in the eukaryotic cell nucleus, and which is involved in oncogenesis and viral infection (By similarity) .

NCBI Gene ID

13144

Swiss Prot

O54784

Accession Number

O54784

Host

Rabbit

Reactivity

Mouse

Immunogen

This Mouse Dapk3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 255-282 amino acids from the Central region of mouse Dapk3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

51 kDa

Fragment

Rabbit Ig

Symbol

Dapk3

NCBI Official Name

Death-associated protein kinase 3

NCBI Organism

Mus musculus

Background Reference 01

Chang, A.N., et al. J. Biol. Chem. 285 (8) :5122-5126 (2010)

Background Reference 02

Ohbayashi, N., et al. Biochem. Biophys. Res. Commun. 372 (4) :708-712 (2008)

Background Reference 03

Wooldridge, A.A., et al. J. Biol. Chem. 283 (17) :11850-11859 (2008)

Background Reference 04

Shoval, Y., et al. PLoS Genet. 3 (10) :1884-1893 (2007)

Other Product Names

Death-associated protein kinase 3, DAP kinase 3, DAP-like kinase, Dlk, MYPT1 kinase, ZIP-kinase, Dapk3, Zipk

Tested Applications

WB, IHC-P

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

KN414474 1 Kit

COL27A1 Human Gene Knockout Kit (CRISPR)

Ask

View Details

HY-124204 1 Each

LY 274614

Ask

View Details

128451-FITC 100 µL

IL23A (Interleukin-23 Subunit alpha, IL-23 Subunit alpha, IL-23-A, Interleukin-23 Subunit p19, IL-23p19, SGRF, UNQ2498/PRO5798, MGC79388, P19, SGRF) (FITC)

Ask

View Details

E28PE5086 100 µL

DLX4 (10Q12) Mouse Monoclonal antibody

Ask

View Details

PVT31833 2 µg

pEnCMV-JOSD2-3XMyc Plasmid

Ask

View Details

MBS1333068-01 0.02 mg (E-Coli)

Recombinant Deinococcus geothermalis Probable rRNA maturation factor (Dgeo_1273)

Ask

View Details