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PAX7 Antibody

Product Specifications

Background

This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

5081

Swiss Prot

P23759

Accession Number

P23759

Host

Rabbit

Reactivity

Human

Immunogen

This PAX7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-210 amino acids from the Central region of human PAX7.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-920

Calculated Molecular Weight

57 kDa

Fragment

Rabbit Ig

Symbol

PAX7

NCBI Official Name

Paired box protein Pax-7

NCBI Organism

Homo sapiens

Background Reference 01

Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)

Background Reference 02

Williamson, D., et al. J. Clin. Oncol. 28 (13) :2151-2158 (2010)

Background Reference 03

Xynos, A., et al. Stem Cells 28 (5) :965-973 (2010)

Background Reference 04

Edwards, T.L., et al. Ann. Hum. Genet. 74 (2) :97-109 (2010)

Other Product Names

Paired box protein Pax-7, HuP1, PAX7, HUP1

Tested Applications

WB, IHC-P

Protein ID

8247951

Physical Properties

Liquid

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